Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) analysis.
MALDI mass spectrometry provides analysis of non-volatile, soluble, and insoluble analytes. MALDI (Matrix Assisted Laser Desorption Ionization) is useful for samples such as biomolecules (proteins, sugars, peptides) and large organic molecules (polymers, dendrimers).
MALDI mass spectrometry applications include molecular weight determination, molecular weight distribution, proteomics, pharmaceuticals and more. Samples analyzed include polymers, lipids, oligosaccharides, phosphopeptides, bacteria, and small molecules.
MALDI-TOF is available from Intertek laboratories in the US or the UK and provides a high mass range (up to 100,000 Da), high mass resolution and high mass accuracy.